From the International Medical Informatics Association

eTOC for 10 Articles: ACI – Applied Clinical Informatics 2011;2 (1)

New articles are available for the eJournal ACI – Applied Clinical Informatics – an official eJournal of IMIA and AMDIS. The first TEN articles of Volume 2(1) of 2011 are now available at The first six were previously posted at, and so the latest four are listed below.

In addition, the ACI News items are updated every Wednesday and all articles from Volume 0 (2009) and Volume 1(1) (2010) are available as free downloads.

Creation of a Hyponatremia Registry Supported by an Industry-Derived Quality Control Methodology
Research Article
D. Giunta (1), N. Fuentes (1), V. Pazo (1), M. L. Posadas-Martìnez (1), H. Michellangelo (1), G. Waisman (1), F. González Bernaldo de Quirós (1)
(1) Hospital Italiano De Buenos Aires, Area de Investigación en Medicina Interna, Argentina
ACI 2011 2 1: 86-93
Clinical registries are a valuable resource for characterizing diseases and conditions. In the case of hyponatremia, a common and complex condition, no registries have yet been developed and published in the literature. In this article, the authors describe the development of a hyponatremia registry in a single hospital, reviewing the methodology to ensure quality of the registry. The process may have applications in the development of other registries.

A trial of inpatient indication based prescribing during computerized order entry with medications commonly used off-label
Research Article
S. M. Walton (1), W. L. Galanter (2), H. Rosencranz (3), D. Meltzer (4), R. S. Stafford (5), F. Tiryaki (6), D. Sarne (7)
(1) Department of Pharmacy Administration, College of Pharmacy, Chicago, IL; (2) Departments of Medicine and Pharmacy Practice, Chicago, IL; (3) Department of Medicine, Section of General Internal Medicine, Chicago, IL; (4) Dept of Medicine, Section of Hospital Medicine, UC, Chicago, IL; (5) Stanford Prevention Research Center, Stanford University, Medical School Office, Stanford, CA; (6) Department of Pharmacy Administration, College of Pharmacy, UIC, Chicago, IL; (7) Department of Medicine, Section of Endocrinology, Diabetes and Metabolism, Chicago, IL
ACI 2011 2 1: 94-103
Matching prescribed medications to indications in inpatient settings is gaining attention as a means of improving evidence-based medicine and facilitating comparative effectiveness research. Little research has been done in this area, though, and few computerized physician order entry systems include prompts requiring indications match to the prescribed medications. In this study, the authors identified three medications that have common off-label uses in inpatient settings, and evaluate a CPOE alert mechanism requiring medication order indication.

Electronic Medical Record Prompts for Lab Orders in Patients Initiating Statins
Research Article
D. G. Carroll (1, 2), C. Alexander (1), E. A. Radford (2), J. Leeper (1), D. N. Carroll (2)
(1) Tuscaloosa, AL; (2) Auburn, AL
ACI 2011 2 1: 104-115
In 2006, the IOM issued a report that showed at least one quarter of all medication related injuries are preventable. This study assessed the impact of a hybrid intrusive-nonintrusive alert system in an electronic medical record on adherence to recommended baseline and follow up laboratory monitoring for statin therapy. The results suggest an improvement in adherence to recommendations for follow up monitoring.

Unlocking Data for Clinical Research – The German i2b2 Experience
Case Report
Special Topic TMF
T. Ganslandt (1), S. Mate (2), K. Helbing (3), U. Sax (3, 4), H. U. Prokosch (1, 2)
(1) Center for Medical Information and Communication, Erlangen University Hospital, Erlangen, Germany; (2) Chair of Medical Informatics, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany; (3) Department of Medical Informatics, University Medical Center Göttingen, Göttingen, Germany; (4) Division of Information Technology, University Medical Center Göttingen, Göttingen, Germany
ACI 2011 2 1: 116-127
Data from clinical care is increasingly seen as a valuable research resource. The NIH developed the i2b2 platform to integrate clinical care data for research in the United States. In this study, researchers in Germany assessed the applicability of the i2b2 platform to the German context, including the useability of the collected data and enhanced privacy protection for the data.

For further information on this peer-reviewed eJournal, go to

Further materials of interest from the same publishers are to be found in the journal Methods of Information on Medicine and in the IMIA Yearbook of Medical Informatics.

If you have any questions or feedback do not hesitate to contact Schattauer by sending an e-mail to

ACI makes active use of social media tools and can be found at:, and

March 31, 2011 - Posted by | IMIA, journals | , , , , , , ,

Sorry, the comment form is closed at this time.

%d bloggers like this: